How's your microbiota? Let's check your urine

Blood. 2015 Oct 1;126(14):1641-2. doi: 10.1182/blood-2015-08-661504.


In this issue of Blood, Weber and colleagues demonstrate that in the first 10 days following allogeneic hematopoietic transplantation, urinary 3-indoxyl sulfate is a biomarker of intestinal microbiota health and predicts reduced intestinal graft-versus-host disease (GVHD) and treatment-related mortality, as well as improved overall survival.

Publication types

  • Comment

MeSH terms

  • Female
  • Gastrointestinal Microbiome / physiology*
  • Graft vs Host Disease / microbiology*
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Indican / urine*
  • Male


  • Indican