The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis

Mol Cell. 2015 Oct 1;60(1):4-6. doi: 10.1016/j.molcel.2015.09.014.


In this issue, Fang and Bartel (2015) report the identification of novel sequence and structural features of human pri-miRNAs, which--together with previously identified sequence motifs--define a unifying model of mammalian pri-miRNAs and advances the de novo design of artificial pri-miRNAs.

Publication types

  • Comment

MeSH terms

  • Computational Biology / methods*
  • Humans
  • MicroRNAs / metabolism*
  • RNA Precursors / chemistry*


  • MicroRNAs
  • RNA Precursors