Phototherapy of Mycosis Fungoides

Dermatol Clin. 2015 Oct;33(4):697-702. doi: 10.1016/j.det.2015.05.005. Epub 2015 Aug 1.

Abstract

Therapies based on ultraviolet light have long been established in mycosis fungoides (MF). They have traditionally included whole-body ultraviolet light B, both broad-band and narrow-band, and psoralen plus ultraviolet A. Phototherapy may be applied alone in early stage MF or in combination with systemic therapy in refractory early stage MF and advanced MF. This article reviews the most frequently used forms of phototherapy for MF with emphasis on efficacy, safety, and practical considerations.

Keywords: Mycosis fungoides; Narrow-band ultraviolet light B; Phototherapy; Psoralen plus ultraviolet A; Ultraviolet A; Ultraviolet light B.

Publication types

  • Review

MeSH terms

  • Humans
  • Mycosis Fungoides / drug therapy
  • Mycosis Fungoides / radiotherapy
  • Mycosis Fungoides / therapy*
  • PUVA Therapy / methods
  • Phototherapy / methods*
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / therapy*
  • Treatment Outcome
  • Ultraviolet Therapy / methods