Segmental patterns of neuronal development in the chick hindbrain

Nature. 1989 Feb 2;337(6206):424-8. doi: 10.1038/337424a0.


Identification of specific neuronal populations and their projections in the developing hindbrain reveals a segmental organization in which pairs of metameric epithelial units cooperate to generate the repeating sequence of cranial branchiomotor nerves. Neurogenesis also follows a two-segment repeat, suggesting parallels with insect pattern formation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axons / physiology
  • Cell Differentiation
  • Chick Embryo
  • Cranial Nerves / cytology
  • Cranial Nerves / embryology
  • Fluorescent Antibody Technique
  • Immunoenzyme Techniques
  • Microscopy, Electron
  • Microscopy, Electron, Scanning
  • Neurons / cytology
  • Neurons / physiology*
  • Rhombencephalon / cytology
  • Rhombencephalon / embryology*
  • Time Factors