PfAlba1: master regulator of translation in the malaria parasite

Evelien M Bunnik; Karine G Le Roch

doi:10.1186/s13059-015-0795-x

PfAlba1: master regulator of translation in the malaria parasite

Genome Biol. 2015 Oct 8:16:221. doi: 10.1186/s13059-015-0795-x.

Authors

Evelien M Bunnik¹, Karine G Le Roch²

Affiliations

¹ Department of Cell Biology and Neuroscience, Institute for Integrative Genome Biology, Center for Disease Vector Research, University of California Riverside, 900 University Avenue, Riverside, CA, 92521, USA.
² Department of Cell Biology and Neuroscience, Institute for Integrative Genome Biology, Center for Disease Vector Research, University of California Riverside, 900 University Avenue, Riverside, CA, 92521, USA. karine.leroch@ucr.edu.

Abstract

During the asexual replication cycle of the malaria parasite Plasmodium falciparum, the RNA-binding protein PfAlba1 binds and stabilizes a subset of transcripts for translation at a later time point.Please see related Research article: http://www.genomebiology.com/2015/16/1/212.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Humans
Malaria, Falciparum / genetics*
Plasmodium falciparum / genetics*
Protein Biosynthesis*
Protozoan Proteins / genetics*
RNA-Binding Proteins / genetics*

Substances

Protozoan Proteins
RNA-Binding Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding