An innovative approach in osteoporosis opportunistic screening by the dental practitioner: the use of cervical vertebrae and cone beam computed tomography with its viewer program

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Nov;120(5):651-9. doi: 10.1016/j.oooo.2015.08.008. Epub 2015 Aug 22.

Abstract

Objectives: To investigate the use of cone beam computed tomography (CBCT) for predicting osteoporosis based on the cervical vertebrae CBCT-derived radiographic density (RD) using the CBCT-viewer program.

Study design: CBCT scans (WhiteFox, de Gotzen S.r.l device, distributed by Satelec-Acteon Group, Italy) and dual-energy X-ray absorptiometry examinations of 38 women who participated in an earlier investigation were examined. A coronal slice, subjectively determined from the cervical vertebrae, was selected and the RD as gray values for the first and second vertebrae, and the dens was calculated by using CBCT-viewer software (WhiteFox imaging).

Results: The CBCT-derived RD values of the dens and the left part of the first cervical vertebra showed the strongest correlation coefficients (r=0.7, 0.6; P<.001) and the highest sensitivity (76.9%, 70%), specificity (92%, 92.9%), and accuracy (90.8%, 86.4%) in predicting osteoporosis in the lumbar vertebrae and the femoral neck, respectively.

Conclusions: CBCT-derived RD of cervical vertebrae can predict osteoporosis status using a CBCT-viewer program. This finding should be confirmed on other CBCT devices.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Body Mass Index
  • Bone Density
  • Cervical Vertebrae / diagnostic imaging*
  • Cone-Beam Computed Tomography / methods*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Middle Aged
  • Osteoporosis / diagnostic imaging*
  • Predictive Value of Tests
  • Risk Factors
  • Sensitivity and Specificity