The focal electroretinogram in the clinical assessment of macular disease

Ophthalmology. 1989 Jan;96(1):109-14. doi: 10.1016/s0161-6420(89)32944-7.


Focal electroretinograms (ERGs) were obtained from the fovea in 142 eyes with a variety of macular diseases and 50 age-matched eyes with acuity loss in which macular disease was ruled out. Across all eyes, the accuracy rate of discriminating macular disease from other causes of acuity loss was 87%. Among all eyes with macular disease, the sensitivity rate of the focal ERG to the presence of macular disease was 85%. Log focal ERG amplitude was significantly correlated with log Snellen acuity, except in those eyes with macular holes. The sensitivity rate increased to 94% when eyes with 20/40 or greater acuity and eyes with macular holes were excluded.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Electroretinography*
  • Humans
  • Macula Lutea*
  • Middle Aged
  • Retinal Diseases / diagnosis*
  • Retinal Perforations / diagnosis
  • Sensitivity and Specificity
  • Vision Disorders / physiopathology
  • Vision Tests
  • Visual Acuity