Canine hyperlipidaemia

J Small Anim Pract. 2015 Oct;56(10):595-605. doi: 10.1111/jsap.12396.


Hyperlipidaemia refers to an increased concentration of lipids in the blood. Hyperlipidaemia is common in dogs and has recently emerged as an important clinical condition that requires a systematic diagnostic approach and appropriate treatment. Hyperlipidaemia can be either primary or secondary to other diseases. Secondary hyperlipidaemia is the most common form in dogs, and it can be a result of endocrine disorders, pancreatitis, cholestasis, protein-losing nephropathy, obesity, as well as other conditions and the use of certain drugs. Primary hyperlipidaemia is less common in the general canine population but it can be very common within certain breeds. Hypertriglyceridaemia of Miniature Schnauzers is the most common form of primary hyperlipidaemia in dogs but other breeds are also affected. Possible complications of hyperlipidaemia in dogs include pancreatitis, liver disease, atherosclerosis, ocular disease and seizures. Management of primary hyperlipidaemia in dogs is achieved by administration of ultra low-fat diets with or without the administration of lipid lowering drugs such as omega-3 fatty acids, fibrates, niacin and statins.

Publication types

  • Review

MeSH terms

  • Animals
  • Atherosclerosis / complications
  • Atherosclerosis / veterinary
  • Biliary Tract Diseases / complications
  • Biliary Tract Diseases / veterinary
  • Dog Diseases / diagnosis*
  • Dog Diseases / etiology
  • Dog Diseases / therapy*
  • Dogs
  • Eye Diseases / complications
  • Eye Diseases / veterinary
  • Hyperlipidemias / complications
  • Hyperlipidemias / diagnosis
  • Hyperlipidemias / therapy
  • Hyperlipidemias / veterinary*
  • Insulin Resistance
  • Lipid Metabolism
  • Lipoproteins / metabolism
  • Liver Diseases / complications
  • Liver Diseases / veterinary
  • Metabolic Networks and Pathways
  • Pancreatitis / complications
  • Pancreatitis / veterinary


  • Lipoproteins