Structures, physicochemical properties, and applications of T-Hg(II)-T, C-Ag(I)-C, and other metallo-base-pairs

Yoshiyuki Tanaka; Jiro Kondo; Vladimír Sychrovský; Jakub Šebera; Takenori Dairaku; Hisao Saneyoshi; Hidehito Urata; Hidetaka Torigoe; Akira Ono

doi:10.1039/c5cc02693h

Structures, physicochemical properties, and applications of T-Hg(II)-T, C-Ag(I)-C, and other metallo-base-pairs

Chem Commun (Camb). 2015 Dec 21;51(98):17343-60. doi: 10.1039/c5cc02693h.

Authors

Yoshiyuki Tanaka¹, Jiro Kondo², Vladimír Sychrovský³, Jakub Šebera⁴, Takenori Dairaku⁵, Hisao Saneyoshi⁶, Hidehito Urata⁷, Hidetaka Torigoe⁸, Akira Ono⁶

Affiliations

¹ Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihama-Boji, Yamashirocho, Tokushima, Tokushima 980-8578, Japan. tanakay@ph.bunri-u.ac.jp and Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8578, Japan.
² Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.
³ Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, Flemingovo náměstí 2, 16610, Praha 6, Czech Republic.
⁴ Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i, Flemingovo náměstí 2, 16610, Praha 6, Czech Republic and Institute of Physics, Academy of Sciences of the Czech Republic, v.v.i, Na Slovance 2, CZ-182 21 Prague 8, Czech Republic.
⁵ Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8578, Japan.
⁶ Department of Material & Life Chemistry, Kanagawa University, 3-27-1 Rokkakubashi, Kanagawa-ku, Yokohama, Kanagawa 221-8686, Japan. akiraono@kanagawa-u.ac.jp.
⁷ Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
⁸ Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan.

PMID: 26466090
DOI: 10.1039/c5cc02693h

Abstract

Recently, metal-mediated base-pairs (metallo-base-pairs) have been studied extensively with the aim of exploring novel base-pairs; their structures, physicochemical properties, and applications have been studied. This trend has become more evident after the discovery of Hg(II)-mediated thymine-thymine (T-Hg(II)-T) and Ag(I)-mediated cytosine-cytosine (C-Ag(I)-C) base-pairs. In this article, we focus on the basic science and applications of these metallo-base-pairs, which are composed of natural bases.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Base Pairing
Coordination Complexes / chemistry*
Cytosine / chemistry
Mercury / chemistry*
Silver / chemistry*
Thymine / chemistry

Substances

Coordination Complexes
Silver
Cytosine
Mercury
Thymine