High compared with standard dose lipase pancreatic supplement

Arch Dis Child. 1989 Jan;64(1):143-5. doi: 10.1136/adc.64.1.143.


Cotazym-S-Forte, a new pancreatic supplement containing 10,000 BP units of lipase activity per capsule, was compared with a standard dose pancreatin supplement (Pancrease) with 5000 BP units lipase activity in a randomised crossover trial. The number of capsules of Cotazym-S-Forte administered was half the usual number of Pancrease capsules and was associated with the same degree of fat absorption as Pancrease.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Cystic Fibrosis / drug therapy*
  • Cystic Fibrosis / metabolism
  • Delayed-Action Preparations
  • Dietary Fats / metabolism
  • Drug Administration Schedule
  • Female
  • Humans
  • Infant
  • Lipase / administration & dosage*
  • Male
  • Random Allocation


  • Delayed-Action Preparations
  • Dietary Fats
  • Lipase