Solitary intraocular lymphoma as an initial presentation of widespread disease

Arch Ophthalmol. 1989 Mar;107(3):395-7. doi: 10.1001/archopht.1989.01070010405034.


A patient presented with a large peripapillary choroidal mass as the initial manifestation of widespread, poorly differentiated, large cell lymphoma. The choroidal tumor had clinical and ultrasonographic characteristics of a uveal malignant melanoma. A systemic evaluation and fine-needle aspiration biopsy specimens of the abdomen and choroid established the diagnosis of a lymphoma. On rare occasion, other neoplasms can simulate the diagnostic pattern of uveal melanoma, and fine-needle aspiration biopsy can be crucial in establishing the correct diagnosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abdominal Neoplasms / diagnosis
  • Abdominal Neoplasms / pathology
  • Aged
  • Biopsy, Needle
  • Choroid Neoplasms / diagnosis*
  • Choroid Neoplasms / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Lymphoma / diagnosis*
  • Lymphoma / pathology
  • Male
  • Melanoma / diagnosis
  • Ultrasonography
  • Uveal Neoplasms / diagnosis