Soft tissue tumors of the sinonasal tract

Semin Diagn Pathol. 2016 Mar;33(2):81-90. doi: 10.1053/j.semdp.2015.09.009. Epub 2015 Sep 9.

Abstract

Primary soft tissue tumors arising in the sinonasal tract are rare. While many mesenchymal neoplasms have been reported in the nasal cavity, sinuses, and nasopharynx, few are distinctive to this anatomic region. Some tumor types are relatively more common in this area, such as schwannoma and rhabdomyosarcoma. Nasopharyngeal angiofibroma and sinonasal hemangiopericytoma are unique entities of the sinonasal tract, as well as the recently characterized biphenotypic sinonasal sarcoma. This review discusses the clinical, morphologic, and immunohistochemical features and currently known molecular data of the more frequently encountered soft tissue tumors of the sinonasal tract.

Keywords: Sarcoma; Sinonasal; Soft tissue tumors.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biopsy
  • Humans
  • Immunohistochemistry
  • Nasal Cavity / chemistry
  • Nasal Cavity / pathology*
  • Neoplasms, Connective and Soft Tissue / chemistry
  • Neoplasms, Connective and Soft Tissue / classification
  • Neoplasms, Connective and Soft Tissue / pathology*
  • Nose Neoplasms / chemistry
  • Nose Neoplasms / classification
  • Nose Neoplasms / pathology*
  • Paranasal Sinus Neoplasms / chemistry
  • Paranasal Sinus Neoplasms / classification
  • Paranasal Sinus Neoplasms / pathology*
  • Prognosis

Substances

  • Biomarkers, Tumor