Optical phantoms with adjustable subdiffusive scattering parameters

J Biomed Opt. 2015 Oct;20(10):105008. doi: 10.1117/1.JBO.20.10.105008.

Abstract

A new epoxy-resin-based optical phantom system with adjustable subdiffusive scattering parameters is presented along with measurements of the intrinsic absorption, scattering, fluorescence, and refractive index of the matrix material. Both an aluminium oxide powder and a titanium dioxide dispersion were used as scattering agents and we present measurements of their scattering and reduced scattering coefficients. A method is theoretically described for a mixture of both scattering agents to obtain continuously adjustable anisotropy values g between 0.65 and 0.9 and values of the phase function parameter γ in the range of 1.4 to 2.2. Furthermore, we show absorption spectra for a set of pigments that can be added to achieve particular absorption characteristics. By additional analysis of the aging, a fully characterized phantom system is obtained with the novelty of g and γ parameter adjustment.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption, Radiation
  • Diffusion
  • Equipment Design
  • Equipment Failure Analysis
  • Light*
  • Phantoms, Imaging*
  • Reproducibility of Results
  • Scattering, Radiation*
  • Sensitivity and Specificity
  • Spectrum Analysis / instrumentation*
  • Tomography, Optical / instrumentation*