Update on Antibiotic Prophylaxis for Genitourinary Procedures in Patients with Artificial Joint Replacement and Artificial Heart Valves

Urol Clin North Am. 2015 Nov;42(4):441-7. doi: 10.1016/j.ucl.2015.06.003.


Infection of artificial joint replacements and heart valves is an uncommon but serious complication encountered anytime after the implantation of these prostheses. It is known that bacteremia can lead to infection of a prosthetic device. However, there is no strong evidence to correlate urologic procedures with the development of periprosthetic joint infection or prosthetic valve endocarditis. Therefore, antibiotic prophylaxis for the prevention of endocarditis is not recommended in patients undergoing urologic procedures. However, guidelines regarding prophylaxis to prevent infection of an artificial joint in the setting of a genitourinary procedure are more varied.

Keywords: Antibiotic prophylaxis; Arthroplasty; Bacteremia; Endocarditis; Urologic surgical procedures.

Publication types

  • Review

MeSH terms

  • Antibiotic Prophylaxis*
  • Bacteremia / prevention & control*
  • Endocarditis, Bacterial / prevention & control*
  • Heart Valve Prosthesis
  • Humans
  • Joint Prosthesis
  • Practice Guidelines as Topic
  • Prosthesis-Related Infections / prevention & control*
  • Urogenital Surgical Procedures / adverse effects*