Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide

J Law Med Ethics. Fall 2015;43(3):486-501. doi: 10.1111/jlme.12291.

Abstract

Both bioethics and law have governed human genomics by distinguishing research from clinical practice. Yet the rise of translational genomics now makes this traditional dichotomy inadequate. This paper pioneers a new approach to the ethics of translational genomics. It maps the full range of ethical approaches needed, proposes a "layered" approach to determining the ethics framework for projects combining research and clinical care, and clarifies the key role that return of results can play in advancing translation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genomics / ethics*
  • Humans
  • Translational Medical Research / ethics*