Opinion of the Scientific Committee on Consumer Safety (SCCS)--Opinion on the safety of the use of β-arbutin in cosmetic products

SCCS; Gisela H Degen

doi:10.1016/j.yrtph.2015.10.008

Opinion of the Scientific Committee on Consumer Safety (SCCS)--Opinion on the safety of the use of β-arbutin in cosmetic products

Regul Toxicol Pharmacol. 2015 Dec;73(3):866-7. doi: 10.1016/j.yrtph.2015.10.008. Epub 2015 Oct 19.

Authors

SCCS¹; Gisela H Degen²

Collaborators

SCCS:
U Bernauer, P J Coenraads, G H Degen, M Dusinska, W Lilienblum, E Nielsen, T Platzek, S C Rastogi, C Rousselle, J van Benthem, A Luch, A Bernard, A M Giménez-Arnau, T Vanhaecke

Affiliations

¹ SCCS Secretariat at the European Commission, Directorate General for Health and Food Safety, 11, rue E. Ruppert, L-2920 Luxembourg, Luxembourg. Electronic address: SANTE-C2-SCCS@ec.europa.eu.
² Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany.

PMID: 26482403
DOI: 10.1016/j.yrtph.2015.10.008

Abstract

The SCCS considers the use of β-arbutin to be safe for consumers in cosmetic products in a concentration up to 7% in face creams provided that the contamination of hydroquinone in the cosmetic formulations remain below 1 ppm. A potential combined use of β-arbutin and other hydroquinone releasing substances in cosmetic products has not been evaluated in this Opinion.

Keywords: CAS: 497-76-7; EC: 207-850-3; Regulation 1223/2009; SCCS; Scientific opinion; β-arbutin.

Publication types

Guideline

MeSH terms

Administration, Cutaneous
Animals
Arbutin / administration & dosage
Arbutin / adverse effects*
Consumer Product Safety / standards*
Cosmetics / administration & dosage
Cosmetics / adverse effects*
Dose-Response Relationship, Drug
Humans
Hydroquinones / administration & dosage
Hydroquinones / adverse effects
Risk Assessment
Risk Factors

Substances

Cosmetics
Hydroquinones
Arbutin
hydroquinone