First case of infectious endocarditis caused by Parvimonas micra

Anaerobe. 2015 Dec;36:53-5. doi: 10.1016/j.anaerobe.2015.10.007. Epub 2015 Oct 17.


P. micra is an anaerobic Gram-positive cocci, and a known commensal organism of the human oral cavity and gastrointestinal tract. Although it has been classically described in association with endodontic disease and peritonsillar infection, recent reports have highlighted the role of P. micra as the primary pathogen in the setting of invasive infections. In its most recent taxonomic classification, P. micra has never been reported causing infectious endocarditis in humans. Here, we describe a 71 year-old man who developed severe native valve endocarditis complicated by aortic valvular destruction and perivalvular abscess, requiring emergent surgical intervention. Molecular sequencing enabled identification of P. micra.

Keywords: 16S ribosomal RNA; Gram-positive anaerobic cocci; Infectious endocarditis; Parvimonas micra; Peptostreptococcus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Endocarditis / diagnosis
  • Endocarditis / microbiology*
  • Gram-Positive Bacterial Infections / diagnosis
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Male
  • Peptostreptococcus / genetics
  • Peptostreptococcus / isolation & purification*
  • Peptostreptococcus / physiology