Functionalized nanomaterials: are they effective to perform gene delivery to difficult-to-transfect cells with no cytotoxicity?

Nanoscale. 2015 Nov 21;7(43):18036-43. doi: 10.1039/c5nr04173b.


Nanodiamonds (NDs), multiwalled carbon nanotubes (MWCNTs) and gold nanorods (NRs) can be functionalized to promote gene delivery to hard-to-transfect cells with higher transfection efficiency than cationic lipids, and inducing less cell death.

MeSH terms

  • Animals
  • Cell Line
  • Mice
  • Nanostructures / chemistry*
  • Nanostructures / ultrastructure
  • Transfection / methods*