Comparison of the image qualities of filtered back-projection, adaptive statistical iterative reconstruction, and model-based iterative reconstruction for CT venography at 80 kVp

Eur Radiol. 2016 Jul;26(7):2055-63. doi: 10.1007/s00330-015-4060-1. Epub 2015 Oct 20.


Purpose: To evaluate the subjective and objective qualities of computed tomography (CT) venography images at 80 kVp using model-based iterative reconstruction (MBIR) and to compare these with those of filtered back projection (FBP) and adaptive statistical iterative reconstruction (ASIR) using the same CT data sets.

Materials and methods: Forty-four patients (mean age: 56.1 ± 18.1) who underwent 80 kVp CT venography (CTV) for the evaluation of deep vein thrombosis (DVT) during 4 months were enrolled in this retrospective study. The same raw data were reconstructed using FBP, ASIR, and MBIR. Objective and subjective image analysis were performed at the inferior vena cava (IVC), femoral vein, and popliteal vein.

Results: The mean CNR of MBIR was significantly greater than those of FBP and ASIR and images reconstructed using MBIR had significantly lower objective image noise (p < .001). Subjective image quality and confidence of detecting DVT by MBIR group were significantly greater than those of FBP and ASIR (p < .005), and MBIR had the lowest score for subjective image noise (p < .001).

Conclusion: CTV at 80 kVp with MBIR was superior to FBP and ASIR regarding subjective and objective image qualities.

Key points: • MBIR provides superior image quality compared with FBP and ASIR • CTV at 80kVp with MBIR improves diagnostic confidence in diagnosing DVT • CTV at 80kVp with MBIR presents better image quality with low radiation.

Keywords: Diagnosis; Lower extremity; Multidetector computed tomography; Radiography; Veins.

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Female
  • Femoral Vein / diagnostic imaging
  • Humans
  • Male
  • Middle Aged
  • Phlebography / methods*
  • Popliteal Vein / diagnostic imaging
  • Radiation Dosage*
  • Radiographic Image Enhancement / methods*
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Radiographic Image Interpretation, Computer-Assisted / standards
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*
  • Tomography, X-Ray Computed / standards
  • Vena Cava, Inferior / diagnostic imaging
  • Venous Thrombosis / diagnostic imaging*