Invasive Pneumococcal Disease 3 Years after Introduction of 10-Valent Pneumococcal Conjugate Vaccine, the Netherlands

Abstract

Three years after a 7-valent pneumococcal conjugate vaccine was replaced by a 10-valent pneumococcal conjugate vaccine in the Netherlands, we observed a decrease in incidence of invasive pneumococcal disease caused by Streptococcus pneumoniae serotypes 1, 5, and 7F. Our data do not support or exclude cross-protection against serotype 19A.

Keywords: 10-valent pneumococcal conjugate vaccine; 7-valent pneumococcal conjugate vaccine; IPD; PCV10; PCV7; Streptococcus pneumoniae; incidence; invasive pneumococcal disease; streptococci; surveillance; the Netherlands; vaccine switching.