Autonomic nervous system dysfunction in severe tetanus: current perspectives

Crit Care Med. 1989 Apr;17(4):371-5. doi: 10.1097/00003246-198904000-00015.


The enigma of autonomic nervous system dysfunction in severe tetanus is discussed in the light of recent and older evidence concerning the nature and action of tetanus toxin, its clinical effects, and therapy. Some suggestions for the pathogenesis and management of the cardiovascular disturbances are made.

Publication types

  • Review

MeSH terms

  • Autonomic Nervous System Diseases / etiology*
  • Autonomic Nervous System Diseases / therapy
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / therapy
  • Humans
  • Tetanus / complications*
  • Tetanus Toxin


  • Tetanus Toxin