The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans

Lancet Infect Dis. 2016 Jan;16(1):125-129. doi: 10.1016/S1473-3099(15)00298-4. Epub 2015 Oct 19.


Oral cholera vaccination could be deployed in a diverse range of situations from cholera-endemic areas and locations of humanitarian crises, but no clear consensus exists. The supply of licensed, WHO-prequalified cholera vaccines is not sufficient to meet endemic and epidemic needs worldwide and so prioritisation is needed. We have developed a scenario approach to systematically classify situations in which oral cholera vaccination might be useful. Our scenario approach distinguishes between five types of cholera epidemiology based on experiences from around the world and provides evidence that we hope will spur the development of detailed guidelines on how and where oral cholera vaccines could, and should, be most rationally deployed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Oral
  • Cholera / prevention & control*
  • Cholera Vaccines / administration & dosage*
  • Communicable Disease Control / legislation & jurisprudence*
  • Communicable Disease Control / organization & administration
  • Emergencies
  • Health Policy*
  • Humans
  • World Health Organization


  • Cholera Vaccines