Measles in Italy: Co-circulation of B3 variants during 2014

J Med Virol. 2016 Jun;88(6):1081-5. doi: 10.1002/jmv.24416. Epub 2015 Nov 6.


In 2013, the majority of the WHO/EUR countries reported an annual incidence of >1 case per one million population indicating that the elimination target is far from being met. Thus, there is the urgent need to uncover and analyze chains of measles virus (MV) transmission with the objective to identify vulnerable groups and avoid possible routes of introduction of MV variants in the European population. The analysis of molecular epidemiology of MV B3 strains identified in 2014 has shown that four different variants co-circulated in Italy, including the strain that caused a cruise-line ship outbreak at the beginning of the year.

Keywords: endemic infection; epidemiology; evolution; genetic variability; measles virus; virus classification.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Outbreaks
  • Dried Blood Spot Testing
  • Genetic Variation*
  • Genotype
  • Humans
  • Incidence
  • Italy / epidemiology
  • Measles / epidemiology*
  • Measles / ethnology
  • Measles / transmission
  • Measles / virology*
  • Measles virus / classification
  • Measles virus / genetics*
  • Measles virus / physiology
  • Phylogeny
  • RNA, Viral / genetics
  • Urine / virology


  • RNA, Viral