Corticosteroids: Triamcinolone, Dexamethasone and Fluocinolone

Dev Ophthalmol. 2016:55:221-31. doi: 10.1159/000431198. Epub 2015 Oct 26.

Abstract

Steroids have been extensively used to treat macular edema due to diabetic retinopathy, venous occlusive disease, ocular inflammation and, to a lesser extent, also in some cases of choroidal neovascularization. The various intraocular steroids that have been employed include dexamethasone, triamcinolone and fluocinolone. During the past few years, new drug delivery methods for corticosteroids have been developed and are now part of our therapeutic armamentarium. This chapter provides a brief description of the pharmacology, efficacy and adverse effects associated with the use of steroids in various retinal diseases.

Publication types

  • Review

MeSH terms

  • Dexamethasone / administration & dosage
  • Dexamethasone / adverse effects
  • Dexamethasone / therapeutic use
  • Drug Delivery Systems
  • Fluocinolone Acetonide / administration & dosage
  • Fluocinolone Acetonide / adverse effects
  • Fluocinolone Acetonide / analogs & derivatives
  • Fluocinolone Acetonide / therapeutic use
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects
  • Glucocorticoids / therapeutic use*
  • Humans
  • Macular Edema / drug therapy*
  • Triamcinolone / administration & dosage
  • Triamcinolone / adverse effects
  • Triamcinolone / therapeutic use

Substances

  • Glucocorticoids
  • Fluocinolone Acetonide
  • Triamcinolone
  • Dexamethasone
  • fluocinolone