A Risk Model for Surgical Site Infection in the Gastric Cancer Surgery Using Data of 790 Patients

Dig Surg. 2015;32(6):472-9. doi: 10.1159/000440703. Epub 2015 Oct 28.

Abstract

Background: Understanding risk factors of surgical site infections (SSIs) in gastrectomy is important to provide the best treatment for the patients with gastric cancer.

Methods: This is a retrospective observational study using the medical records of 790 patients with gastrectomy from 2005 through 2009. SSIs were classified into incisional SSIs (iSSIs) and organ/space SSIs (o/sSSIs).

Results: iSSIs and o/sSSIs were detected in 41 (5.2%) patients and 68 (8.6%) patients, respectively. Open surgery was the only independent risk factor (p = 0.028) for iSSIs, while open surgery (p = 0.004), concurrent splenectomy (p < 0.001), operative time ≥220 min (p = 0.009), preoperative body mass index ≥20.8 kg/m2 (p = 0.004) and male gender (p = 0.028) were the independent risk factors for o/sSSIs. We created a risk model for o/sSSIs using these independent risk factors. The C-index model discrimination was 0.84 (p < 0.001), and the calibration of the models demonstrated a linear correlation between the predicted and observed probability.

Conclusion: We reported the risk factors of SSIs for gastrectomy. The risk model developed in this study for o/sSSIs pertaining to gastric cancer surgery would contribute to provide guidance for the development of best practices.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Area Under Curve
  • Body Mass Index
  • Female
  • Gastrectomy / adverse effects*
  • Gastrectomy / methods
  • Gastrectomy / statistics & numerical data*
  • Humans
  • Length of Stay / statistics & numerical data
  • Logistic Models
  • Male
  • Middle Aged
  • Operative Time
  • ROC Curve
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Splenectomy / adverse effects
  • Stomach Neoplasms / surgery*
  • Surgical Wound Infection / etiology*