Warfighters require a range of physical capabilities to meet the demands of the military profession, and physical training must address performance along an entire continuum, depending on individual needs and mission requirements. Strength and power capabilities are needed for optimal performance of anaerobic tasks such as heavy load carriage, sprinting under load, and maneuvering over uneven terrain. For optimal performance, soldiers must also be able to recover from mission demands and strenuous training. The demands placed on a soldier can result in a chronic stress, leading to decreased mission performance, increased injury risk, and increased susceptibility to illness. These factors are exacerbated by inappropriate training strategies such as overemphasis on endurance exercise combined with other stressors such as lack of sleep or inadequate nutrition. Chronic stress has been linked to overreaching/overtraining and to the development of comorbidities such as metabolic syndrome, insulin resistance, and hypertension and has adverse effects on memory and cognitive function. Resistance exercise is an effective method to improve warfighter physical performance and resilience to stress, thereby impacting mission readiness. Resistance exercise in particular confers many benefits to include increased strength and power, improved body composition, and protective effects on tendons, ligaments, and bone. Physically fit individuals not only benefit from improved mission performance but also are more resilient to operational stressors faced during combat. Ultimately, resilient soldiers are better able to cope with the physical and mental demands of the military profession and over the long term will perform better while maintaining health and well-being.