Relieving pain and distress during venipuncture: Pilot study of the Japan Environment and Children's Study (JECS)

Pediatr Int. 2015 Oct;57(5):1044-7. doi: 10.1111/ped.12818.


Pain management for needle-related procedures is poor in Japan. In many countries the use of lidocaine/prilocaine cream for the relief of pain associated with venipuncture has been approved. In children, a psychological approach has also been shown to be effective in reducing pain with venipuncture. We developed a multidisciplinary procedure that combines a cream (2.5% lidocaine and 2.5% prilocaine) and pharmacological approaches such as preparation, education, positioning and distraction. We evaluated the feasibility and acceptability of the procedure for young children. Among 132 pediatric participants, 58.3% did not cry during venipuncture. According to caregiver questionnaire, 71.9% felt that the multidisciplinary procedure eliminated the fear of needle-related procedures in the children; 90.9% were satisfied with it and 75.8% thought it should be applied to all children undergoing venipuncture. The present results suggest that the multidisciplinary procedure is feasible, acceptable and suitable for use in children undergoing venipuncture.

Keywords: distress; lidocaine/prilocaine cream; pain; psychological intervention in venipuncture.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Japan / epidemiology
  • Male
  • Pain / diagnosis*
  • Pain / epidemiology
  • Pain Management / methods*
  • Pain Measurement / methods*
  • Pilot Projects
  • Prognosis
  • Retrospective Studies