Meningitis and Bacteremia Due to Neisseria cinerea following a Percutaneous Rhizotomy of the Trigeminal Ganglion

M von Kietzell; H Richter; T Bruderer; D Goldenberger; S Emonet; C Strahm

doi:10.1128/JCM.02041-15

Meningitis and Bacteremia Due to Neisseria cinerea following a Percutaneous Rhizotomy of the Trigeminal Ganglion

J Clin Microbiol. 2016 Jan;54(1):233-5. doi: 10.1128/JCM.02041-15. Epub 2015 Oct 28.

Authors

M von Kietzell¹, H Richter², T Bruderer³, D Goldenberger⁴, S Emonet⁵, C Strahm⁶

Affiliations

¹ Department of Internal Medicine, Division of Infectious Diseases, Cantonal Hospital St. Gallen, St. Gallen, Switzerland matthias.vonkietzell@kssg.ch.
² Department of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
³ Center of Laboratory Medicine, Department of Bacteriology, Mycology and Parasitology, St. Gallen, Switzerland.
⁴ Clinical Microbiology, University Hospital, Basel, Switzerland.
⁵ Service of Infectious Diseases, Geneva University Hospitals & Faculty of Medicine, University of Geneva, Geneva, Switzerland.
⁶ Department of Internal Medicine, Division of Infectious Diseases, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.

Abstract

Neisseria cinerea is a human commensal. The first known case of meningitis and bacteremia due to Neisseria cinerea following percutaneous glycerol instillation of the trigeminal ganglion is reported. Conventional phenotypic methods and complete 16S RNA gene sequencing accurately identified the pathogen. Difficulties in differentiation from pathogenic neisseriae are discussed.

Publication types

Case Reports

MeSH terms

Anti-Bacterial Agents / pharmacology
Bacteremia / complications
Bacteremia / diagnosis*
Bacteremia / microbiology
Cluster Analysis
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Head / diagnostic imaging
Humans
Male
Meningitis, Bacterial / complications
Meningitis, Bacterial / diagnosis*
Meningitis, Bacterial / microbiology
Microbial Sensitivity Tests
Middle Aged
Molecular Sequence Data
Neisseria cinerea / classification
Neisseria cinerea / drug effects
Neisseria cinerea / genetics
Neisseria cinerea / isolation & purification*
Neisseriaceae Infections / diagnosis*
Neisseriaceae Infections / microbiology
Neisseriaceae Infections / pathology
Phylogeny
RNA, Ribosomal, 16S / genetics
Rhizotomy / adverse effects
Sequence Analysis, DNA
Tomography, X-Ray Computed
Trigeminal Neuralgia / therapy

Substances

Anti-Bacterial Agents
DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S

Grants and funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sector.