We review recent progress in cancer nanomedicine, including stimulus-responsive drug delivery systems and nanoparticles responding to light for phototherapy or tumor imaging. In addition, several new strategies to improve the circulation of nanoparticles in vivo, tumor penetration, and tumor targeting are discussed. The application of nanomedicine in cancer immunology, a relatively new type of cancer therapy, is also highlighted.
Keywords: PEGylation; cancer immunology; circulation; nanomedicine; nanoparticle; self-immolative polymer; stimulus-responsive drug delivery; triggered drug delivery; tumor penetration; tumor targeting.