Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;41:50-52.
doi: 10.1016/j.ijid.2015.10.022. Epub 2015 Oct 30.

Use of String Test and Stool Specimens to Diagnose Pulmonary Tuberculosis

Free PMC article

Use of String Test and Stool Specimens to Diagnose Pulmonary Tuberculosis

Andrew R DiNardo et al. Int J Infect Dis. .
Free PMC article


Background: The Xpert MTB/RIF (MTB/RIF) test has advanced the field of tuberculosis (TB) diagnostics; however, depending on age and HIV status, 10-85% of individuals with presumed pulmonary TB (PTB) are unable to produce sputum.

Methods: The feasibility of using MTB/RIF and culture on stool and string test specimens from 13 adult patients with presumed PTB was studied.

Results: The string test was well tolerated with a median Wong Baker Faces score of 2. The string test had 100% sensitivity and specificity by MTB/RIF and 87.5% sensitivity and 100% specificity by culture. In stool, Mycobacterium tuberculosis DNA was detected in all cases of culture-confirmed PTB.

Conclusion: The string test and stool provide diagnostic specimens that warrant further investigation.

Keywords: Stool; String test; Tuberculosis; Xpert MTB/RIF.

Similar articles

See all similar articles

Cited by 5 articles


    1. Steingart KR, Ng V, Henry M, Hopewell PC, Ramsay A, Cunningham J, et al. Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis. 2006;6:664–74. - PubMed
    1. Davis JL, Cattamanchi A, Cuevas LE, Hopewell PC, Steingart KR. Diagnostic accuracy of same-day microscopy versus standard microscopy for pulmonary tuberculosis: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13:147–54. - PMC - PubMed
    1. Steingart KR, Sohn H, Schiller I, Kloda LA, Boehme CC, Pai M, et al. Xpert(R) MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2013;1:CD009593. - PMC - PubMed
    1. Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, et al. Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology. J Clin Microbiol. 2010;48:229–37. - PMC - PubMed
    1. Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM. Systematic review and meta-analysis: Xpert MTB/RIF for the diagnosis of pulmonary tuberculosis, peripheral lymph node TB and TB meningitis in children. WHO Expert Group Meeting on the Use of Xpert MTB/RIF in TB Control in Low and Middle-Income Settings.. WHO Expert Meeting; Veyrier-du-Lac. May 20-21, 2013.