The challenge of preoperative identification of uterine myomas: Is ultrasound trustworthy? A prospective cohort study

Arch Gynecol Obstet. 2016 Jun;293(6):1235-41. doi: 10.1007/s00404-015-3937-1. Epub 2015 Nov 2.

Abstract

Purpose: To correlate preoperative ultrasound examination with intraoperative and anatomo-pathological findings, including estimation of number, localization and size of uterine myomas, uterine diameters and volume.

Methods: A prospective study on 126 women undergoing surgery for uterine myomatosis at Campus Bio-medico between May 2013 and April 2014. The patients were divided into two groups: one submitted to hysterectomy and the other submitted to open myomectomy. Ultrasound scans were performed 1 day before surgery by the same expert sonographer. The number of myomas at ultrasound was compared to intraoperative visualization and anatomo-pathological findings. Wilcoxon Test was applied to compare data registered with each technique.

Results: There was no significant difference between the number of myomas recorded at visualization and at ultrasound, while there was a significant difference between visualization and anatomo-pathology (p = 0.0006). The analysis showed a non-significant difference between myoma number at ultrasound and at anatomo-pathology in the two groups, if the number of myomas was less than or equal to six. Contrarily, we observed a significant difference if the number of myomas was more than six (p = 0.003).

Conclusions: Our data show that ultrasound has limits in identifying the exact number of uterine myomas. This mapping is particularly needed in a minority of patients with usually desiring fertility who need a debulking procedure due to the large size and/or number of myomas or myoma location causing symptomatology. In patients with more than six myomas, voluminous uterus, a second-level examination such as Magnetic Resonance may be helpful.

Keywords: Hysterectomy; Myomectomy; Preoperative ultrasound; Prospective study; Ultrasound; Uterine myomas.

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Female
  • Humans
  • Hysterectomy
  • Leiomyoma / diagnostic imaging*
  • Leiomyoma / pathology
  • Leiomyoma / surgery
  • Magnetic Resonance Imaging
  • Middle Aged
  • Prospective Studies
  • Ultrasonography
  • Uterine Myomectomy / methods
  • Uterine Neoplasms / diagnostic imaging*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery