MetaNetX/MNXref--reconciliation of metabolites and biochemical reactions to bring together genome-scale metabolic networks

Nucleic Acids Res. 2016 Jan 4;44(D1):D523-6. doi: 10.1093/nar/gkv1117. Epub 2015 Nov 2.


MetaNetX is a repository of genome-scale metabolic networks (GSMNs) and biochemical pathways from a number of major resources imported into a common namespace of chemical compounds, reactions, cellular compartments--namely MNXref--and proteins. The website ( provides access to these integrated data as well as a variety of tools that allow users to import their own GSMNs, map them to the MNXref reconciliation, and manipulate, compare, analyze, simulate (using flux balance analysis) and export the resulting GSMNs. MNXref and MetaNetX are regularly updated and freely available.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Chemical*
  • Genome*
  • Metabolic Networks and Pathways / genetics*
  • Molecular Structure
  • Software