Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Guideline
. 2015 Sep 4;12(2):272.
doi: 10.2390/biecoll-jib-2015-272.

Synthetic Biology Open Language (SBOL) Version 2.0.0

Guideline

Synthetic Biology Open Language (SBOL) Version 2.0.0

Bryan Bartley et al. J Integr Bioinform. .

Abstract

Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond.

Similar articles

  • Synthetic Biology Open Language (SBOL) Version 2.2.0.
    Cox RS, Madsen C, McLaughlin JA, Nguyen T, Roehner N, Bartley B, Beal J, Bissell M, Choi K, Clancy K, Grünberg R, Macklin C, Misirli G, Oberortner E, Pocock M, Samineni M, Zhang M, Zhang Z, Zundel Z, Gennari JH, Myers C, Sauro H, Wipat A. Cox RS, et al. J Integr Bioinform. 2018 Apr 2;15(1):20180001. doi: 10.1515/jib-2018-0001. J Integr Bioinform. 2018. PMID: 29605823 Free PMC article.
  • Synthetic Biology Open Language (SBOL) Version 2.1.0.
    Beal J, Cox RS, Grünberg R, McLaughlin J, Nguyen T, Bartley B, Bissell M, Choi K, Clancy K, Macklin C, Madsen C, Misirli G, Oberortner E, Pocock M, Roehner N, Samineni M, Zhang M, Zhang Z, Zundel Z, Gennari J, Myers C, Sauro H, Wipat A. Beal J, et al. J Integr Bioinform. 2016 Dec 18;13(3):291. doi: 10.2390/biecoll-jib-2016-291. J Integr Bioinform. 2016. PMID: 28187407
  • Synthetic Biology Open Language (SBOL) Version 2.3.
    Madsen C, Goñi Moreno A, P U, Palchick Z, Roehner N, Atallah C, Bartley B, Choi K, Cox RS, Gorochowski T, Grünberg R, Macklin C, McLaughlin J, Meng X, Nguyen T, Pocock M, Samineni M, Scott-Brown J, Tarter Y, Zhang M, Zhang Z, Zundel Z, Beal J, Bissell M, Clancy K, Gennari JH, Misirli G, Myers C, Oberortner E, Sauro H, Wipat A. Madsen C, et al. J Integr Bioinform. 2019 Jun 13;16(2):20190025. doi: 10.1515/jib-2019-0025. J Integr Bioinform. 2019. PMID: 31199770 Free PMC article.
  • Synthetic Biology Open Language Visual (SBOL Visual) Version 2.1.
    Madsen C, Goni Moreno A, Palchick Z, P U, Roehner N, Bartley B, Bhatia S, Bhakta S, Bissell M, Clancy K, Cox RS, Gorochowski T, Grunberg R, Luna A, McLaughlin J, Nguyen T, Le Novere N, Pocock M, Sauro H, Scott-Brown J, Sexton JT, Stan GB, Tabor JJ, Voigt CA, Zundel Z, Myers C, Beal J, Wipat A. Madsen C, et al. J Integr Bioinform. 2019 Jun 13;16(2):20180101. doi: 10.1515/jib-2018-0101. J Integr Bioinform. 2019. PMID: 31199768 Free PMC article. Review.
  • A standard-enabled workflow for synthetic biology.
    Myers CJ, Beal J, Gorochowski TE, Kuwahara H, Madsen C, McLaughlin JA, Mısırlı G, Nguyen T, Oberortner E, Samineni M, Wipat A, Zhang M, Zundel Z. Myers CJ, et al. Biochem Soc Trans. 2017 Jun 15;45(3):793-803. doi: 10.1042/BST20160347. Biochem Soc Trans. 2017. PMID: 28620041 Review.
See all similar articles

Cited by 3 articles

Publication types

Feedback