White matter low attenuation on CT in Alzheimer's disease

Arch Gerontol Geriatr. 1989 Jan;8(1):95-104. doi: 10.1016/0167-4943(89)90074-5.


White matter low attenuation (WMLA) was seen on CT in 19.7% of 61 patients with probable Alzheimer's disease. Presence of WMLA was associated with higher age, more severe degree of dementia, and increased CSF/serum albumin ratio, but not with cardiovascular disorders. WMLA on CT might be related to minor vascular events, or Alzheimer patients with WMLA could even constitute their own subtype.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Alzheimer Disease / diagnostic imaging*
  • Blood-Brain Barrier
  • Brain / diagnostic imaging*
  • Female
  • Humans
  • Male
  • Tomography, X-Ray Computed*