Limited Role of Sinus CT in the Management of Febrile Pediatric HSCT Recipients

J Pediatr Hematol Oncol. 2016 Aug;38(6):e186-8. doi: 10.1097/MPH.0000000000000464.


Management guidelines have questioned the role of sinus computed tomography (CT). We reviewed 55 febrile episodes with sinus CT during 1 year after admission for hematopoietic stem cell transplant to determine predictive factors for positive sinus CT and the impact on management. Positive sinus CT findings were seen in 42% of febrile episodes. No characteristics were identified as predictors of a positive sinus CT. No other infectious source was identified in 17% of positive sinus CT episodes, with no pharmacotherapy modifications based solely on a positive sinus CT. Sinus CT should be examined in multicenter groups to develop practice guidelines.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Child
  • Fever / diagnostic imaging*
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Tomography, X-Ray Computed / methods*