Nobel lecture in physiology or medicine--1988. Selective inhibitors of dihydrofolate reductase

In Vitro Cell Dev Biol. 1989 Apr;25(4):303-10. doi: 10.1007/BF02624591.
No abstract available

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Bacteria / enzymology
  • Folic Acid / analogs & derivatives
  • Folic Acid / metabolism*
  • Folic Acid Antagonists*
  • History, 20th Century
  • Humans
  • Methotrexate / pharmacology
  • Molecular Conformation
  • Molecular Structure
  • Nobel Prize
  • Protein Conformation
  • Tetrahydrofolate Dehydrogenase / history
  • Tetrahydrofolate Dehydrogenase / metabolism
  • Tetrahydrofolates / metabolism
  • Trimethoprim / pharmacology

Substances

  • Folic Acid Antagonists
  • Tetrahydrofolates
  • dihydrofolate
  • Folic Acid
  • Trimethoprim
  • Tetrahydrofolate Dehydrogenase
  • Methotrexate