Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Nov 6;350(6261):636-7.
doi: 10.1126/science.aad6303.

DRUG DISCOVERY. A new dawn for cataracts

Affiliations
Comment

DRUG DISCOVERY. A new dawn for cataracts

Roy A Quinlan. Science. .
No abstract available

PubMed Disclaimer

Comment on

  • Lanosterol reverses protein aggregation in cataracts.
    Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Jefferson J, Perry P, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Zhao L, et al. Nature. 2015 Jul 30;523(7562):607-11. doi: 10.1038/nature14650. Epub 2015 Jul 22. Nature. 2015. PMID: 26200341
  • Pharmacological chaperone for α-crystallin partially restores transparency in cataract models.
    Makley LN, McMenimen KA, DeVree BT, Goldman JW, McGlasson BN, Rajagopal P, Dunyak BM, McQuade TJ, Thompson AD, Sunahara R, Klevit RE, Andley UP, Gestwicki JE. Makley LN, et al. Science. 2015 Nov 6;350(6261):674-7. doi: 10.1126/science.aac9145. Science. 2015. PMID: 26542570 Free PMC article.

Similar articles

  • Ophthalmology: Cataracts dissolved.
    Hejtmancik JF. Hejtmancik JF. Nature. 2015 Jul 30;523(7562):540-1. doi: 10.1038/nature14629. Epub 2015 Jul 22. Nature. 2015. PMID: 26200338 No abstract available.
  • Lanosterol reverses protein aggregation in cataracts.
    Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Jefferson J, Perry P, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Zhao L, et al. Nature. 2015 Jul 30;523(7562):607-11. doi: 10.1038/nature14650. Epub 2015 Jul 22. Nature. 2015. PMID: 26200341
  • Effect of lanosterol on human cataract nucleus.
    Shanmugam PM, Barigali A, Kadaskar J, Borgohain S, Mishra DK, Ramanjulu R, Minija CK. Shanmugam PM, et al. Indian J Ophthalmol. 2015 Dec;63(12):888-90. doi: 10.4103/0301-4738.176040. Indian J Ophthalmol. 2015. PMID: 26862091 Free PMC article.
  • Pharmacological approaches to restoring lens transparency: Real world applications.
    Skinner C, Miraldi Utz V. Skinner C, et al. Ophthalmic Genet. 2017 May-Jun;38(3):201-205. doi: 10.1080/13816810.2016.1214971. Epub 2016 Sep 20. Ophthalmic Genet. 2017. PMID: 27648776 Review.
  • Peptide-based treatment strategies for cataract.
    Cetinel S, Unsworth L, Montemagno C. Cetinel S, et al. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S73-6. doi: 10.1097/IJG.0000000000000111. J Glaucoma. 2014. PMID: 25275913 Review.

Cited by

LinkOut - more resources