Transcriptional control of cell fate in the stomatal lineage

Curr Opin Plant Biol. 2016 Feb;29:1-8. doi: 10.1016/j.pbi.2015.09.008. Epub 2015 Nov 7.

Abstract

The Arabidopsis stomatal lineage is a microcosm of development; it undergoes selection of precursor cells, asymmetric and stem cell-like divisions, cell commitment and finally, acquisition of terminal cell fates. Recent transcriptomic approaches revealed major shifts in gene expression accompanying each fate transition, and mechanistic analysis of key bHLH transcription factors, along with mathematical modeling, has begun to unravel how these major shifts are coordinated. In addition, stomatal initiation is proving to be a tractable model for defining the genetic and epigenetic basis of stable cell identities and for understanding the integration of environmental responses into developmental programs.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / growth & development*
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism
  • Basic Helix-Loop-Helix Transcription Factors / genetics*
  • Basic Helix-Loop-Helix Transcription Factors / metabolism
  • Cell Differentiation*
  • Gene Expression Regulation, Plant*
  • Models, Biological
  • Plant Stomata / genetics
  • Plant Stomata / growth & development

Substances

  • Arabidopsis Proteins
  • Basic Helix-Loop-Helix Transcription Factors