Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients

Simon A Joosse; Klaus Pantel

doi:10.1016/j.ccell.2015.10.007

Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients

Cancer Cell. 2015 Nov 9;28(5):552-554. doi: 10.1016/j.ccell.2015.10.007.

Authors

Simon A Joosse¹, Klaus Pantel²

Affiliations

¹ Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
² Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. Electronic address: pantel@uke.de.

PMID: 26555171
DOI: 10.1016/j.ccell.2015.10.007

Abstract

Real-time monitoring of changes in cells or cell products released from malignant lesions into the blood has opened new diagnostic avenues ("liquid biopsy"). In this issue of Cancer Cell, Best and colleagues describe that tumor-associated blood platelets provide specific information on the location and molecular composition of the primary tumor.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Biomarkers, Tumor / genetics*
Blood Platelets / metabolism*
Female
Humans
Male
Neoplasms / genetics*
Signal Transduction / genetics*

Substances

Biomarkers, Tumor