A life-threatening presentation of eosinophilic granulomatosis with polyangiitis

J Cardiovasc Med (Hagerstown). 2016 Dec;17 Suppl 2:e109-e111. doi: 10.2459/JCM.0000000000000330.

Abstract

: Necrotizing eosinophilic myocarditis (NEM) is a life-threatening condition that needs rapid diagnosis by endomyocardial biopsy and hemodynamic support usually by mechanical circulatory systems. We present the case of a 25-year-old Caucasian man who developed a refractory cardiogenic shock due to a NEM that was supported with a peripheral veno-arterial extracorporeal membrane oxygenation associated with intravenous steroids and recovered after 2 weeks. Further instrumental investigations lead to the final diagnosis of NEM as first presentation of eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome), remarking the importance of identifying the systemic disorder that usually triggers the eosinophilic damage of the myocardium.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Adult
  • Biopsy
  • Churg-Strauss Syndrome / complications*
  • Churg-Strauss Syndrome / diagnosis
  • Churg-Strauss Syndrome / therapy
  • Extracorporeal Membrane Oxygenation
  • Granulomatosis with Polyangiitis / complications*
  • Granulomatosis with Polyangiitis / diagnosis
  • Granulomatosis with Polyangiitis / therapy
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Magnetic Resonance Imaging
  • Male
  • Myocarditis / diagnosis
  • Myocarditis / etiology*
  • Myocarditis / therapy
  • Myocardium / pathology
  • Necrosis
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / etiology*
  • Shock, Cardiogenic / therapy
  • Steroids / administration & dosage
  • Time Factors
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • Steroids