A Case Report: Consecutive Cranial Neuropathies Following the Use of Phosphodiesterase-5 Inhibitors

Suzanne W van Landingham; Eric L Singman

doi:10.3368/aoj.65.1.109

A Case Report: Consecutive Cranial Neuropathies Following the Use of Phosphodiesterase-5 Inhibitors

Am Orthopt J. 2015:65:109-14. doi: 10.3368/aoj.65.1.109.

Authors

Suzanne W van Landingham¹, Eric L Singman²

Affiliations

¹ From the Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland.
² From the Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland. esingma1@jhmi.edu.

PMID: 26564936
DOI: 10.3368/aoj.65.1.109

Abstract

We report a patient who suffered consecutive cranial neuropathies where each event was immediately preceded by the use of oral PDE-5 inhibitors. A discussion of the etiology of the events including possible interaction with other medications is included.

Keywords: Cialis/tadalafil; Viagra/sildenafil; diplopia; ischemic cranial neuropathy; phosphodiesterase-5 inhibitors; sixth cranial nerve palsy; third cranial nerve palsy.

Publication types

Case Reports

MeSH terms

Aged
Cranial Nerve Diseases / chemically induced*
Cranial Nerve Diseases / diagnosis
Erectile Dysfunction / drug therapy
Humans
Male
Phosphodiesterase 5 Inhibitors / adverse effects*
Phosphodiesterase 5 Inhibitors / therapeutic use
Sildenafil Citrate / adverse effects
Sildenafil Citrate / therapeutic use
Tadalafil / adverse effects
Tadalafil / therapeutic use

Substances

Phosphodiesterase 5 Inhibitors
Tadalafil
Sildenafil Citrate