Abstract
A new study reveals that an exotic lipid, phosphatidylthreonine, makes up a substantial proportion of the membrane of a widespread human parasite and is essential for its virulence. Read the Research Article.
MeSH terms
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Animals
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Cell Membrane / metabolism*
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Glycerophospholipids / metabolism*
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Humans
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Lipid Bilayers / metabolism
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Lipid Metabolism*
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Models, Biological*
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Protozoan Proteins / metabolism*
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Species Specificity
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Threonine / analogs & derivatives*
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Threonine / metabolism
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Toxoplasma / enzymology
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Toxoplasma / growth & development
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Toxoplasma / metabolism*
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Toxoplasma / pathogenicity
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Transferases (Other Substituted Phosphate Groups) / metabolism*
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Virulence
Substances
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Glycerophospholipids
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Lipid Bilayers
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Protozoan Proteins
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phosphatidylthreonine
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Threonine
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Transferases (Other Substituted Phosphate Groups)