Is there really an increased risk of early colorectal cancer in women with BRCA1 pathogenic mutations?

Clin Genet. 2016 Mar;89(3):399. doi: 10.1111/cge.12687. Epub 2015 Nov 14.

Authors

D G Evans¹, T Clancy¹, J Hill², M Tischkowitz³

Affiliations

¹ Department of Genomic Medicine, MAHSC, Institute of Human Development, University of Manchester, St. Mary's Hospital, Manchester, UK.
² Department of Colorectal Surgery, MAHSC, Institute of Human Development, University of Manchester, St. Mary's Hospital, Manchester, UK.
³ Department of Medical Genetics, University of Cambridge, Cambridge, UK.

PMID: 26566797
DOI: 10.1111/cge.12687

No abstract available

Publication types

Letter
Comment

MeSH terms

Colorectal Neoplasms / epidemiology*
Colorectal Neoplasms / genetics*
Genes, BRCA1*
Genes, BRCA2*
Genetic Predisposition to Disease*
Humans
Mutation*