High-Output Heart Failure Caused by Thyrotoxicosis and Beriberi

Crit Care Nurs Clin North Am. 2015 Dec;27(4):499-510. doi: 10.1016/j.cnc.2015.07.004. Epub 2015 Sep 2.


High-output heart failure is not seen as commonly as low-output heart failure and some of the typical guideline recommendations may not benefit patients with high-output failure. High-output failure is caused by several diseases, including thyrotoxicosis and beriberi, highlighted in this article. Thyrotoxicosis, caused by excessive thyroid hormone production, has profound hemodynamic effects. Wet beriberi, affecting predominately the cardiovascular system, is caused by severe thiamine deficiency, most commonly seen in patients with chronic alcoholism or poor nutrition from other causes. Prompt recognition of these infrequently seen syndromes is essential. This article outlines the medical treatment and nursing care needed to return these patients to a normal state.

Keywords: Beriberi; High-output heart failure; Shoshin beriberi; Thiamine deficiency; Thionamides; Thyrotoxicosis; Wet beriberi.

Publication types

  • Review

MeSH terms

  • Beriberi / complications*
  • Beriberi / diagnosis
  • Beriberi / drug therapy
  • Cardiac Output / physiology
  • Disease Management
  • Heart Failure / diagnosis
  • Heart Failure / drug therapy*
  • Heart Failure / etiology
  • Hemodynamics / physiology
  • Humans
  • Nursing Care
  • Thyrotoxicosis / complications*
  • Thyrotoxicosis / diagnosis
  • Thyrotoxicosis / drug therapy