Adolescent Varicoceles and Infertility

Endocrinol Metab Clin North Am. 2015 Dec;44(4):835-42. doi: 10.1016/j.ecl.2015.07.007. Epub 2015 Aug 24.


Varicoceles are associated with testicular atrophy and abnormal spermatogenesis. Varicocele-related testicular damage is thought to be progressive in nature. Adult varicoceles are common in men with infertility, and varicocele repair in this population has demonstrated improved semen parameters and paternity outcomes. However, without solid objective endpoints (reproducible semen analyses, paternity), the indications for adolescent varicocele repair remain controversial. Given the controversy surrounding adolescent varicocele management, it is not surprising that surveys of pediatric urologists have revealed a lack of consensus on diagnostic approaches, treatment decisions, and operative approaches.

Keywords: Adolescent; Infertility; Semen analysis; Varicocele; Varicocelectomy.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Humans
  • Infertility, Male / etiology*
  • Male
  • Varicocele / complications*
  • Varicocele / surgery