Hepatitis B among Asian Americans: Prevalence, progress, and prospects for control

World J Gastroenterol. 2015 Nov 14;21(42):11924-30. doi: 10.3748/wjg.v21.i42.11924.


After tobacco use, chronic hepatitis B (CHB) viral infections are the most important cause of cancer globally in that 1 out of 3 individuals have been infected with the hepatitis B virus (HBV). Though infection rates are low (< 1%) in the United States, Asian Americans who comprise about 6% of the population experience about 60% of the CHB burden. This paper reviews the magnitude of hepatitis B (HBV) burden among Asian Americans and the progress being made to mitigate this burden, primarily through localized, community-based efforts to increase screening and vaccination among Asian American children, adolescents, and adults. This review brings to light that despite the numerous community-based screening efforts, a vast majority of Asian Americans have not been screened and that vaccination efforts, particularly for adults, are sub-optimal. Greater efforts to integrate screenings by providers within existing healthcare systems are urged. Evidence-based strategies are offered to implement CDC's three major recommendations to control and prevent hepatitis B through targeted screening and enhanced vaccination efforts.

Keywords: Asian Americans; Chronic hepatitis B; Hepatitis B; Vaccination.

Publication types

  • Review

MeSH terms

  • Asian Americans*
  • Hepatitis B Vaccines / therapeutic use
  • Hepatitis B, Chronic / diagnosis
  • Hepatitis B, Chronic / ethnology*
  • Hepatitis B, Chronic / prevention & control
  • Humans
  • Prevalence
  • Prognosis
  • Risk Factors
  • United States / epidemiology
  • Vaccination


  • Hepatitis B Vaccines