Iron overload-related heart failure in a patient with transfusion-dependent myelodysplastic syndrome reversed by intensive combined chelation therapy

Valeria Pinto; Manuela Balocco; Ilaria Ambaglio; Giorgio Derchi; Luca Malcovati; Gian Luca Forni

doi:10.1002/ccr3.407

Iron overload-related heart failure in a patient with transfusion-dependent myelodysplastic syndrome reversed by intensive combined chelation therapy

Clin Case Rep. 2015 Nov;3(11):952-4. doi: 10.1002/ccr3.407. Epub 2015 Oct 21.

Authors

Valeria Pinto¹, Manuela Balocco¹, Ilaria Ambaglio², Giorgio Derchi³, Luca Malcovati², Gian Luca Forni¹

Affiliations

¹ Ematologia-Centro della Microcitemia e Anemie Congenite, Ospedale Galliera Genoa, Italy.
² Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Pavia, Italy.
³ Unità di Cardiologia, Ospedale Galliera Genoa, Italy.

Abstract

Patients with transfusion-dependent myelodysplastic syndromes (MDS) have an increased risk of cardiac events, due to both chronic anemia and iron overload. Here, we report the recovery of cardiac function after an intensive iron chelation therapy in a MDS patient who had developed heart failure due to iron overload.

Keywords: Deferiprone; desferal; heart failure; iron chelation; myelodysplastic syndromes.

Publication types

Case Reports