A single nucleotide TDP-43 mutation within a Taiwanese family: A multifaceted demon

Yu-Wen Cheng; Ming-Jen Lee; Ta-Fu Chen; Ting-Wen Cheng; Ya-Mei Lai; Mau-Sun Hua; Ming-Jang Chiu

doi:10.3109/21678421.2015.1111905

A single nucleotide TDP-43 mutation within a Taiwanese family: A multifaceted demon

Amyotroph Lateral Scler Frontotemporal Degener. 2016;17(3-4):292-4. doi: 10.3109/21678421.2015.1111905. Epub 2015 Nov 19.

Authors

Yu-Wen Cheng¹, Ming-Jen Lee¹, Ta-Fu Chen¹, Ting-Wen Cheng¹, Ya-Mei Lai¹, Mau-Sun Hua², Ming-Jang Chiu^{1

2

3}

Affiliations

¹ a Department of Neurology , National Taiwan University Hospital, College of Medicine, National Taiwan University , Taipei , Taiwan.
² b Department of Psychology, College of Science , National Taiwan University , Taipei.
³ c Institute of Brain and Mind Sciences, College of Medicine , National Taiwan University , Taipei , Taiwan.

PMID: 26581115
DOI: 10.3109/21678421.2015.1111905

No abstract available

Keywords: Amyotrophic lateral sclerosis (ALS); FTLD-ALS; frontotemporal lobar degeneration (FTLD); transactive response DNA binding protein 43 kDa (TDP-43).

Publication types

Case Reports

MeSH terms

Adult
Aged
Brain / diagnostic imaging
DNA Mutational Analysis
DNA-Binding Proteins / genetics*
Family Health*
Female
Frontotemporal Lobar Degeneration / diagnostic imaging
Frontotemporal Lobar Degeneration / genetics*
Humans
Male
Middle Aged
Multifactor Dimensionality Reduction
Neuroimaging
Polymorphism, Single Nucleotide / genetics*
Taiwan / epidemiology

Substances

DNA-Binding Proteins
TARDBP protein, human