Acid-base disorders in critical care medicine

Annu Rev Med. 1989;40:17-29. doi: 10.1146/


In critically ill patients, nonrespiratory (metabolic) alkalosis is the most common acid-base disturbance; it is caused by hypochloremia and/or by hypoproteinemia. Information on the concentration of plasma proteins should be included when evaluating acid-base status.

Publication types

  • Review

MeSH terms

  • Alkalosis / etiology
  • Alkalosis / physiopathology*
  • Chlorides / blood
  • Critical Care*
  • Humans
  • Hypoproteinemia / complications
  • Hypoproteinemia / physiopathology


  • Chlorides