TAILS N-terminomic and proteomic datasets of healthy human dental pulp

Data Brief. 2015 Oct 16;5:542-8. doi: 10.1016/j.dib.2015.10.003. eCollection 2015 Dec.


The Data described here provide the in depth proteomic assessment of the human dental pulp proteome and N-terminome (Eckhard et al., 2015) [1]. A total of 9 human dental pulps were processed and analyzed by the positional proteomics technique TAILS (Terminal Amine Isotopic Labeling of Substrates) N-terminomics. 38 liquid chromatography tandem mass spectrometry (LC-MS/MS) datasets were collected and analyzed using four database search engines in combination with statistical downstream evaluation, to yield the by far largest proteomic and N-terminomic dataset of any dental tissue to date. The raw mass spectrometry data and the corresponding metadata have been deposited in ProteomeXchange with the PXD identifier <PXD002264>; Supplementary Tables described in this article are available via Mendeley Data (10.17632/555j3kk4sw.1).

Keywords: Human dental pulp; N-terminome; Proteome; TAILS N-terminomics; Tandem mass spectrometry.